MersV1, Main, Exploration, bibRecord, 004C95

Histone H2B repression causes cell-cycle-specific arrest in yeast: Effects on chromosomal segregation, replication, and transcription

Identifieur interne : 004C95 ( Main/Exploration ); précédent : 004C94; suivant : 004C96

Histone H2B repression causes cell-cycle-specific arrest in yeast: Effects on chromosomal segregation, replication, and transcription

Auteurs : Min Han [États-Unis] ; Miles Chang [États-Unis] ; Ung-Jin Kim [États-Unis] ; Michael Grunstein [États-Unis]

Source :

Cell [ 0092-8674 ] ; 1987.

RBID : ISTEX:B35722EA7529EAC518C3D6FD4226FCF64234CCAC

English descriptors

Teeft :
- Acad, Biol, Cell cycle, Cell division, Cell number, Cellular processes, Cerevisiae, Channel numbers, Chromatin, Chromosomal, Chromosomal segregation, Chromosome, Chromosome structure, Cold spring harbor, Dapi, Experimental procedures, Full round, Galactose, Gene induction, Glucose, Glucose arrest, Glucose medium, Glucose repression, Grunstein, Hartwell, Hereford, High levels, Histone, Histone mrnas, Histone synthesis, Htbp gene, Hydroxyurea, Lethality, Mhylo2 cells, Mhylop, Mhylop cells, Micrococcal nuclease, Mitosis, Monoclonal antibody, Mrna, Mrna synthesis, Mutant, Mutation, Natl, Northern blot, Nuclear segregation, Nuclease, Nucleosome, Nucleosomes, Phenotype, Plasmid, Proc, Promoter, Replication, Room temperature, Saccharomyces, Saccharomyces cerevisiae, Simian virus, Superhelical, Superhelical density, Terminal phenotype, Time point, Time points, Transcription, Various media, Various times, Wallis, Yeast, Yeast cell cycle, Yeast strain, Yepd.

Abstract

Abstract: To determine which cellular processes are dependent on histones, we blocked histone H2B mRNA synthesis in asynchronously growing yeast after fusing the H2B gene to a repressible GAL10 promoter. Chromosomal segregation, replication, and transcription were then examined. We found that the cells arrested in mitosis, with a cell division cycle (cdc) phenotype. Chromatin structure and nuclear segregation were disrupted. A full round of DNA replication took place after the repression of histone H2B mRNA synthesis. Active transcription and the induction of new transcripts also continued in the arrested cells.

Url:

https://api.istex.fr/ark:/67375/6H6-M2DNHXP9-N/fulltext.pdf

DOI: 10.1016/0092-8674(87)90237-6

Affiliations:

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Le document en format XML

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<term>Cellular processes</term>
<term>Cerevisiae</term>
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Histone H2B repression causes cell-cycle-specific arrest in yeast: Effects on chromosomal segregation, replication, and transcription

Histone H2B repression causes cell-cycle-specific arrest in yeast: Effects on chromosomal segregation, replication, and transcription

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri